Innovation in the genomics field is extremely intense and requires significant up-front investments. The toolbox of sequencing platforms, each with unique features requiring specialised training and leverage extensive cross-functional expertise, is rapidly expanding. The EASIGEN-DS project evolves from two successful EU infrastructure projects that have provided hundreds of researchers with access to cutting-edge DNA sequencing technologies. 

 

The aim of this project is to carry out a design study for a new European Research Infrastructure on Advanced Genomics Technologies, EASIGEN. In order to develop an excellent scientific, technological and operational framework, we will conduct landscape studies, stakeholder consultations, community surveys, as well as proof-of-concept activities. In parallel, we will seek support and commitment from national and EU stakeholders, as well as user communities, through a multi‐faceted dissemination plan. 

 

We envision that EASIGEN will encompass:

1) a Technology Platform that will offer state-of-the-art genomic analysis methods, such as single-cell genomics, spatial genomics and long-read sequencing, as well as population-scale genomics capacity.

2) a Support Platform that will provide standardisation tools, training, co-innovation with industry, and consulting for smaller facilities, including those in widening countries. Both platforms will serve a vast community of users from the health, biomedical and life science fields. 

 

The consortium brings together:

1) a network of eleven genomics facilities with distinct application specialities and a combined sequencing capacity of over 500,000 human genomes per year.

2) four expert partners specialising in data stewardship; ethical, legal and social implications; socio-economic impact and innovation.  

 

The new infrastructure will strengthen the European Research Area, promote interconnections within the ESFRI landscape, and boost an innovative biotechnology-based industry. 

 

This project has received funding from the European Union’s Horizon Europe research and innovation program under grant agreement No HORIZON-INFRA-2024-DEV-01. This reflects only the author's view and the Commission is not responsible for any use that may be made of the information it contains. 

 

THE ROLE OF CNAG  

 

CNAG is the coordinator of this project. As such, we will provide guidance and oversee the implementation of the project, including all related activities, work packages, and deliverables. In addition, CNAG will be responsible for the work carried out in WP1 and WP2, focusing on coordination, communication, and stakeholder engagement, as well as WP6, which covers EASIGEN's management, financial aspects, environmental considerations, and implementation plan.