The landscape of tolerated genetic variation in humans and primates | 2023-06-02 | Gao, H; Hamp, T; Ede, J; Schraiber, JG; McRae, J; Singer-Berk, M; Yang, YS; Dietrich, ASD; Fiziev, PP; Kuderna, LFK; Sundaram, L; Wu, YB; Adhikari, A; (2023). The landscape of tolerated genetic variation in humans and primates. Science, 380(6648), 929-+. DOI: 10.1126/science.abn8197 | https://doi.org/10.1126/science.abn8197 |
Phylogenomic analyses provide insights into primate evolution | 2023-06-02 | Shao, Y; Zhou, L; Li, F; Zhao, L; Zhang, BL; Shao, F; Chen, JW; Chen, CY; Bi, XP; Zhuang, XL; Zhu, HL; Hu, J; Sun, ZY; Li, X; Wang, DP; Rivas-Gonzalez (2023). Phylogenomic analyses provide insights into primate evolution. Science, 380(6648), 913-924. DOI: 10.1126/science.abn6919 | https://doi.org/10.1126/science.abn6919 |
Comparative genomics reveals the hybrid origin of a macaque group | 2023-06-02 | Zhang, BL; Chen, W; Wang, ZF; Pang, W; Luo, MT; Wang, S; Shao, Y; He, WQ; Deng, Y; Zhou, L; Chen, JW; Yang, MM; Wu, YJ; Wang, L; Fernández-Bellon, H; (2023). Comparative genomics reveals the hybrid origin of a macaque group. Science Advances, 9(22), eadd3580-. DOI: 10.1126/sciadv.add3580 | https://doi.org/10.1126/sciadv.add3580 |
Chromosome-level genome assembly of Lilford's wall lizard, Podarcis lilfordi (Gunther, 1874) from the Balearic Islands (Spain) | 2023-06-01 | Gomez-Garrido, J; Cruz, F; Alioto, TS; Feiner, N; Uller, T; Gut, M; Escudero, IS; Tavecchia, G; Rotger, A; Acevedo, KEO; Baldo, L (2023). Chromosome-level genome assembly of Lilford's wall lizard, Podarcis lilfordi (Gunther, 1874) from the Balearic Islands (Spain). Dna Research, 30(3), dsad008-. DOI: 10.1093/dnares/dsad008 | https://doi.org/10.1093/dnares/dsad008 |
Periostin as a blood biomarker of muscle cell fibrosis, cardiomyopathy and disease severity in myotonic dystrophy type 1 | 2023-06-01 | Nguyen, CDL; Jimenez-Moreno, AC; Merker, M; Bowers, CJ; Nikolenko, N; Hentschel, A; Muntefering, T; Isham, A; Ruck, T; Vorgerd, M; Dobelmann, V; Gourd (2023). Periostin as a blood biomarker of muscle cell fibrosis, cardiomyopathy and disease severity in myotonic dystrophy type 1. Journal Of Neurology, 270(6), 3138-3158. DOI: 10.1007/s00415-023-11633-1 | https://doi.org/10.1007/s00415-023-11633-1 |
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin | 2023-05-30 | Garcia-Diaz, C; Pöysti, A; Mereu, E; Clements, MP; Brooks, LJ; Galvez-Cancino, F; Castillo, SP; Tang, WH; Beattie, G; Courtot, L; Ruiz, S; Roncaroli, (2023). Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin. Cell Reports, 42(5), 112472-. DOI: 10.1016/j.celrep.2023.112472 | https://doi.org/10.1016/j.celrep.2023.112472 |
Evaluation of circulating tumor DNA by electropherogram analysis and methylome profiling in high-risk neuroblastomas | 2023-05-12 | Trinidad, EM; Juan-Ribelles, A; Pisano, G; Castel, V; Canete, A; Gut, M; Heath, S; de Mora, JF (2023). Evaluation of circulating tumor DNA by electropherogram analysis and methylome profiling in high-risk neuroblastomas. Frontiers In Oncology, 13(), 1037342-. DOI: 10.3389/fonc.2023.1037342 | https://doi.org/10.3389/fonc.2023.1037342 |
Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+T cells | 2023-05-10 | Kobayashi-Ishihara, M; Smutna, KF; Alonso, FE; Argilaguet, J; Esteve-Codina, A; Geiger, K; Genesca, M; Grau-Exposito, J; Duran-Castells, C; Rogenmoser (2023). Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+T cells. Commun Biol, 6(1), 487-. DOI: 10.1038/s42003-023-04841-y | https://doi.org/10.1038/s42003-023-04841-y |
Identifying miRNA-mRNA regulatory networks on extreme n-6/n-3 polyunsaturated fatty acid ratio expression profiles in porcine skeletal muscle | 2023-05-04 | Manaig, YJY; Criado-Mesas, L; Esteve-Codina, A; Marmol-Sanchez, E; Castello, A; Sanchez, A; Folch, JM (2023). Identifying miRNA-mRNA regulatory networks on extreme n-6/n-3 polyunsaturated fatty acid ratio expression profiles in porcine skeletal muscle. Plos One, 18(5), e0283231-. DOI: 10.1371/journal.pone.0283231 | https://doi.org/10.1371/journal.pone.0283231 |
Evaluation of triple negative breast cancer with heterogeneous immune infiltration | 2023-05-04 | Quintana, A; Arenas, EJ; Bernado, C; Navarro, JF; Gonzalez, J; Esteve-Codina, A; Moline, T; Marti, M; Curigliano, G; Schmid, P; Peg, V; Arribas, J; Co (2023). Evaluation of triple negative breast cancer with heterogeneous immune infiltration. Frontiers In Immunology, 14(), 1149747-. DOI: 10.3389/fimmu.2023.1149747 | https://doi.org/10.3389/fimmu.2023.1149747 |
High ambient temperature impacts on flowering time in Brassica napus through both H2A.Z-dependent and independent mechanisms | 2023-05-01 | Abelenda, JA; Trabanco, N; Del Olmo, I; Pozas, J; Martin-Trillo, MD; Gomez-Garrido, J; Esteve-Codina, A; Pernas, M; Jarillo, JA; Pineiro, M (2023). High ambient temperature impacts on flowering time in Brassica napus through both H2A.Z-dependent and independent mechanisms. Plant Cell And Environment, 46(5), 1427-1441. DOI: 10.1111/pce.14526 | https://doi.org/10.1111/pce.14526 |
A chromosome-level genome assembly enables the identification of the follicule stimulating hormone receptor as the master sex-determining gene in the flatfish Solea senegalensis | 2023-05-01 | de la Herran, R; Hermida, M; Rubiolo, JA; Gomez-Garrido, J; Cruz, F; Robles, F; Navajas-Perez, R; Blanco, A; Villamayor, PR; Torres, D; Sanchez-Quinte (2023). A chromosome-level genome assembly enables the identification of the follicule stimulating hormone receptor as the master sex-determining gene in the flatfish Solea senegalensis. Molecular Ecology Resources, 23(4), 886-904. DOI: 10.1111/1755-0998.13750 | https://doi.org/10.1111/1755-0998.13750 |
Dissecting the Origin of Heterogeneity in Uterine and Ovarian Carcinosarcomas | 2023-05-01 | Sertier, AS; Ferrari, A; Pommier, RM; Treilleux, I; Boyault, S; Devouassoux-Shisheboran, M; Kielbassa, J; Thomas, E; Tonon, L; Le Texier, V; Charreton (2023). Dissecting the Origin of Heterogeneity in Uterine and Ovarian Carcinosarcomas. Cancer Research Communications, 3(5), 830-841. DOI: 10.1158/2767-9764.crc-22-0520 | https://doi.org/10.1158/2767-9764.CRC-22-0520 |
Evolutionary constraint and innovation across hundreds of placental mammals | 2023-04-28 | Christmas, MJ; Kaplow, IM; Genereux, DP; Dong, MX; Hughes, GM; Li, X; Sullivan, PF; Hindle, AG; Andrews, G; Armstrong, JC; Bianchi, M; Breit, AM; Diek (2023). Evolutionary constraint and innovation across hundreds of placental mammals. Science, 380(6643), 366-+. DOI: 10.1126/science.abn3943 | https://doi.org/10.1126/science.abn3943 |
Relating enhancer genetic variation across mammals to complex phenotypes using machine learning | 2023-04-28 | Kaplow, IM; Lawler, AJ; Schäffer, DE; Srinivasan, C; Sestili, HH; Wirthlin, ME; Phan, BN; Prasad, K; Brown, AR; Zhang, XM; Foley, K; Genereux, DP; Kar (2023). Relating enhancer genetic variation across mammals to complex phenotypes using machine learning. Science, 380(6643), 364-+. DOI: 10.1126/SCIENCE.ABM7993 | https://doi.org/10.1126/SCIENCE.ABM7993 |
Integrating gene annotation with orthology inference at scale | 2023-04-28 | Kirilenko, BM; Munegowda, C; Osipova, E; Jebb, D; Sharma, V; Blumer, M; Morales, AE; Ahmed, AW; Kontopoulos, DG; Hilgers, L; Lindblad-Toh, K; Karlsson (2023). Integrating gene annotation with orthology inference at scale. Science, 380(6643), eabn3107-+. DOI: 10.1126/SCIENCE.ABN3107 | https://doi.org/10.1126/SCIENCE.ABN3107 |
The contribution of historical processes to contemporary extinction risk in placental mammals | 2023-04-28 | Wilder, AP; Supple, MA; Subramanian, A; Mudide, A; Swofford, R; Serres-Armero, A; Steiner, C; Koepfli, KP; Genereux, DP; Karlsson, EK; Lindblad-Toh, K (2023). The contribution of historical processes to contemporary extinction risk in placental mammals. Science, 380(6643), 372-+. DOI: 10.1126/science.abn5856 | https://doi.org/10.1126/science.abn5856 |
Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs | 2023-04-28 | Moon, KL; Huson, HJ; Morrill, K; Wang, MS; Li, X; Srikanth, K; Lindblad-Toh, K; Svenson, GJ; Karlsson, EK; Shapiro, B (2023). Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs. Science, 380(6643), eabn5887-. DOI: 10.1126/SCIENCE.ABN5887 | https://doi.org/10.1126/SCIENCE.ABN5887 |
The functional and evolutionary impacts of human-specific deletions in conserved elements | 2023-04-28 | Xue, JR; Mackay-Smith, A; Mouri, K; Garcia, MF; Dong, MX; Akers, JF; Noble, M; Li, X; Lindblad-Toh, K; Karlsson, EK; Noonan, JP; Capellini, TD; Brenna (2023). The functional and evolutionary impacts of human-specific deletions in conserved elements. Science, 380(6643), eabn2253-+. DOI: 10.1126/SCIENCE.ABN2253 | https://doi.org/10.1126/SCIENCE.ABN2253 |
Three-dimensional genome rewiring in loci with human accelerated regions | 2023-04-28 | Keough, KC; Whalen, S; Inoue, F; Przytycki, PF; Fair, T; Deng, CY; Steyert, M; Ryu, H; Lindblad-Toh, K; Karlsson, E; Nowakowski, T; Ahituv, N; Pollen, (2023). Three-dimensional genome rewiring in loci with human accelerated regions. Science, 380(6643), eabm1696-+. DOI: 10.1126/SCIENCE.ABM1696 | https://doi.org/10.1126/SCIENCE.ABM1696 |