With the establishment of this framework agreement, both institutions seek to promote, from a collaborative perspective, the development of genome research in Catalonia, consortium participation in competitive large-scale genome projects, dissemination of scientific advances as well as promotion of...

Recent technological advances allow us to analyse patients all the way down to their proteins and chemicals and their own DNA sequences in just a couple of hours. On the basis of these data, a physician will be able to use a computer to quickly suggest individual advice or therapy: which drugs,...

Next generation sequencing (NGS) allows investigation of populations on a genomic scale, thus facilitating the transition from single marker studies to population genomics.
Sequencing pools of individuals (Pool-seq) is a cost effective alternative to sequencing individuals separately that...

The genome three-dimensional (3D) organization plays important, yet poorlyunderstood roles in gene regulation. Chromosomes assume multiple distinctconformations in relation to the expression status of resident genes andundergo dramatic alterations in higher order structure through the cellcycle....

This five full-day intensive course will cover state-of-the-art statistical methods for detection of genetic loci influencing complex traits. Each day will include discussions of analysis theory and hands-on computer exercises, focusing on the Mendel software package.
This course is designed...

We have investigated in the yeast Saccharomyces cerevisiae the mechanisms by which the Mediator, a 25 subunits complex, stimulates the transcription by RNA polymerase (Pol) II of activated genes. We identified a contact between Pol II and the Mediator in vivo and demonstrated that this contact is...