Autoantibodies neutralizing type I IFNs are present in ∼4% of uninfected individuals over 70 years old and account for ∼20% of COVID-19 deaths | 2021-08-01 | Bastard, P; Gervais, A; Le Voyer, T; Rosain, J; Philippot, Q; Manry, J; Michailidis, E; Hoffmann, HH; Eto, S; Garcia-Prat, M; Bizien, L; Parra-Martíne (2021). Autoantibodies neutralizing type I IFNs are present in ∼4% of uninfected individuals over 70 years old and account for ∼20% of COVID-19 deaths. Science Immunology, 6(62), eabl4340-. DOI: 10.1126/sciimmunol.abl4340 | https://doi.org/10.1126/sciimmunol.abl4340 |
Human tRNAs with inosine 34 are essential to efficiently translate eukarya-specific low-complexity proteins | 2021-07-09 | Torres, AG; Rodríguez-Escribà, M; Marcet-Houben, M; Vieira, HGS; Camacho, N; Catena, H; Recio, MM; Rafels-Ybern, A; Reina, O; Torres, FM; Pardo-Sagant (2021). Human tRNAs with inosine 34 are essential to efficiently translate eukarya-specific low-complexity proteins. Nucleic Acids Research, 49(12), 7011-7034. DOI: 10.1093/nar/gkab461 | https://doi.org/10.1093/nar/gkab461 |
CeLaVi: an interactive cell lineage visualization tool | 2021-07-02 | Salvador-Martinez, I; Grillo, M; Averof, M; Telford, MJ (2021). CeLaVi: an interactive cell lineage visualization tool. Nucleic Acids Research, 49(W1), W80-W85. DOI: 10.1093/nar/gkab325 | https://doi.org/10.1093/nar/gkab325 |
Mechnetor: a web server for exploring protein mechanism and the functional context of genetic variants | 2021-07-02 | Gonzalez-Sanchez, JC; Ibrahim, MFR; Leist, IC; Weise, KR; Russell, RB (2021). Mechnetor: a web server for exploring protein mechanism and the functional context of genetic variants. Nucleic Acids Research, 49(W1), W366-W374. DOI: 10.1093/nar/gkab399 | https://doi.org/10.1093/nar/gkab399 |
An improved MALDI-TOF MS data analysis pipeline for the identification of carbapenemase-producing Klebsiella pneumoniae | 2021-07-01 | Gato, E; Constanso, IP; Candela, A; Galán, F; Rodiño-Janeiro, BK; Arroyo, MJ; Méndez, G; Mancera, L; Alioto, T; Gut, M; Gut, I; Alvarez-Tejado, M; Rod (2021). An improved MALDI-TOF MS data analysis pipeline for the identification of carbapenemase-producing Klebsiella pneumoniae. Journal Of Clinical Microbiology, 59(7), e00800-21-. DOI: 10.1128/JCM.00800-21 | https://doi.org/10.1128/JCM.00800-21 |
Lung microbiome composition and bronchial epithelial gene expression in patients with COPD versus healthy individuals: a bacterial 16S rRNA gene sequencing and host transcriptomic analysis | 2021-07-01 | Ramsheh, MY; Haldar, K; Esteve-Codina, A; Purser, LF; Richardson, M; Müller-Quernheim, J; Greulich, T; Nowinski, A; Barta, I; Stendardo, M; Boschetto, (2021). Lung microbiome composition and bronchial epithelial gene expression in patients with COPD versus healthy individuals: a bacterial 16S rRNA gene sequencing and host transcriptomic analysis. The Lancet Microbe, 2(7), E300-E310. DOI: 10.1016/S2666-5247(21)00035-5 | https://doi.org/10.1016/S2666-5247(21)00035-5 |
Chromosome anchoring in Senegalese sole (Solea senegalensis) reveals sex-associated markers and genome rearrangements in flatfish | 2021-06-29 | Guerrero-Cózar, I; Gomez-Garrido, J; Berbel, C; Martinez-Blanch, JF; Alioto, T; Claros, MG; Gagnaire, PA; Manchado, M (2021). Chromosome anchoring in Senegalese sole (Solea senegalensis) reveals sex-associated markers and genome rearrangements in flatfish. Scientific Reports, 11(1), 13460-. DOI: 10.1038/s41598-021-92601-5 | https://doi.org/10.1038/s41598-021-92601-5 |
Assessment of the gene mosaicism burden in blood and its implications for immune disorders | 2021-06-21 | Solís-Moruno, M; Mensa-Vilaró, A; Batlle-Masó, L; Lobón, I; Bonet, N; Marquès-Bonet, T; Aróstegui, JI; Casals, F (2021). Assessment of the gene mosaicism burden in blood and its implications for immune disorders. Scientific Reports, 11(1), 12940-. DOI: 10.1038/s41598-021-92381-y | https://doi.org/10.1038/s41598-021-92381-y |
Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes | 2021-06-18 | Esteve-Codina, A; Hofer, TP; Burggraf, D; Heiss-Neumann, MS; Gesierich, W; Boland, A; Olaso, R; Bihoreau, MT; Deleuze, JF; Moeller, W; Schmid, O; Arti (2021). Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes. Scientific Reports, 11(1), 12848-. DOI: 10.1038/s41598-021-91742-x | https://doi.org/10.1038/s41598-021-91742-x |
HuConTest: Testing Human Contamination in Great Ape Samples | 2021-06-01 | Kuhlwilm, M; Fontsere, C; Han, SJ; Alvarez-Estape, M; Marques-Bonet, T (2021). HuConTest: Testing Human Contamination in Great Ape Samples. Genome Biology And Evolution, 13(6), evab117-. DOI: 10.1093/gbe/evab117 | https://doi.org/10.1093/gbe/evab117 |
Activity of imipenem/relebactam against a Spanish nationwide collection of carbapenemase-producing Enterobacterales | 2021-06-01 | Vázquez-Ucha, JC; Seoane-Estévez, A; Rodiño-Janeiro, BK; González-Bardanca, M; Conde-Pérez, K; Martínez-Guitián, M; Alvarez-Fraga, L; Arca-Suárez, J; (2021). Activity of imipenem/relebactam against a Spanish nationwide collection of carbapenemase-producing Enterobacterales. Journal Of Antimicrobial Chemotherapy, 76(6), 1498-1510. DOI: 10.1093/jac/dkab043 | https://doi.org/10.1093/jac/dkab043 |
Dual role of integrin alpha-6 in glioblastoma: Supporting stemness in proneural stem-like cells while inducing radioresistance in mesenchymal stem-like cells | 2021-06-01 | Stanzani, E; Pedrosa, L; Bourmeau, G; Anezo, O; Noguera-Castells, A; Esteve-Codina, A; Passoni, L; Matteoli, M; de la Iglesia, N; Seano, G; Martínez-S (2021). Dual role of integrin alpha-6 in glioblastoma: Supporting stemness in proneural stem-like cells while inducing radioresistance in mesenchymal stem-like cells. Cancers, 13(12), 3055-. DOI: 10.3390/cancers13123055 | https://doi.org/10.3390/cancers13123055 |
Variation in predicted COVID-19 risk among lemurs and lorises | 2021-06-01 | Melin, AD; Orkin, JD; Janiak, MC; Valenzuela, A; Kuderna, L; Marrone, F; Ramangason, H; Horvath, JE; Roos, C; Kitchener, AC; Khor, CC; Lim, WK; Lee, J (2021). Variation in predicted COVID-19 risk among lemurs and lorises. American Journal Of Primatology, 83(6), e23255-. DOI: 10.1002/ajp.23255 | https://doi.org/10.1002/ajp.23255 |
Clinical Manifestations in a Girl with NAA10-Related Syndrome and Genotype-Phenotype Correlation in Females | 2021-06-01 | Maini, I; Caraffi, SG; Peluso, F; Valeri, L; Nicoli, D; Laurie, S; Baldo, C; Zuffardi, O; Garavelli, L (2021). Clinical Manifestations in a Girl with NAA10-Related Syndrome and Genotype-Phenotype Correlation in Females. Genes, 12(6), 900-. DOI: 10.3390/genes12060900 | https://doi.org/10.3390/genes12060900 |
Impact of DNA methylation on 3D genome structure | 2021-05-28 | Buitrago, D; Labrador, M; Arcon, JP; Lema, R; Flores, O; Esteve-Codina, A; Blanc, J; Villegas, N; Bellido, D; Gut, M; Dans, PD; Heath, SC; Gut, IG; He (2021). Impact of DNA methylation on 3D genome structure. Nature Communications, 12(1), 3243-. DOI: 10.1038/s41467-021-23142-8 | https://doi.org/10.1038/s41467-021-23142-8 |
Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures | 2021-05-25 | García-Pérez, R; Esteller-Cucala, P; Mas, G; Lobón, I; Di Carlo, V; Riera, M; Kuhlwilm, M; Navarro, A; Blancher, A; Di Croce, L; Gomez-Skarmeta, JL; J (2021). Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures. Nature Communications, 12(1), 3116-. DOI: 10.1038/s41467-021-23397-1 | https://doi.org/10.1038/s41467-021-23397-1 |
SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes | 2021-05-21 | Elosua-Bayes, M; Nieto, P; Mereu, E; Gut, I; Heyn, H (2021). SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes. Nucleic Acids Research, 49(9), e50-. DOI: 10.1093/nar/gkab043 | https://doi.org/10.1093/nar/gkab043 |
The impact of chromosomal fusions on 3D genome folding and recombination in the germ line | 2021-05-20 | Vara, C; Paytuví-Gallart, A; Cuartero, Y; Alvarez-González, L; Marín-Gual, L; Garcia, F; Florit-Sabater, B; Capilla, L; Sanchez-Guillen, RA; Sarrate, (2021). The impact of chromosomal fusions on 3D genome folding and recombination in the germ line. Nature Communications, 12(1), 2981-. DOI: 10.1038/s41467-021-23270-1 | https://doi.org/10.1038/s41467-021-23270-1 |
Prunus persica plant endogenous peptides PpPep1 and PpPep2 cause PTI-like transcriptome reprogramming in peach and enhance resistance to Xanthomonas arboricola pv. pruni | 2021-05-18 | Foix, L; Nadal, A; Zagorscak, M; Ramsak, Z; Esteve-Codina, A; Gruden, K; Pla, M (2021). Prunus persica plant endogenous peptides PpPep1 and PpPep2 cause PTI-like transcriptome reprogramming in peach and enhance resistance to Xanthomonas arboricola pv. pruni. Bmc Genomics, 22(1), 360-. DOI: 10.1186/s12864-021-07571-9 | https://doi.org/10.1186/s12864-021-07571-9 |
The genomic history of the Aegean palatial civilizations | 2021-05-13 | Clemente, F; Unterländer, M; Dolgova, O; Amorim, CEG; Coroado-Santos, F; Neuenschwander, S; Ganiatsou, E; Dávalos, DIC; Anchieri, L; Michaud, F; Winke (2021). The genomic history of the Aegean palatial civilizations. Cell, 184(10), 2565-+. DOI: 10.1016/j.cell.2021.03.039 | https://doi.org/10.1016/j.cell.2021.03.039 |