The Structural Genomics Group studies the molecular mechanisms that regulate cell fate, applying the law of physics and the rules of evolution.
The objective is to develop and apply computational methods for predicting the three-dimensional organization of the genome and the non-coding RNA molecules that act in its regulation. There is a growing appreciation that disruption in normal chromosomal organization through long-range contacts is a reason for human disease including cancer. Therefore, it is necessary to characterize this level of organization of the nucleus.
The Group participates in projects such as 3D Genomics and HoloGenomics for farm industry, focused on unveiling host-microbiota interactions shaping animal production.