TOTAL NO. PUBLICATIONS: 413
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  • Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils

  • Grassi L, Pourfarzad F, Ullrich S, Merkel A, Were F, Carrillo-de-Santa-Pau E, Yi G, Hiemstra IH, Tool ATJ, Mul E, Perner J, Janssen-Megens E, Berentsen K, Kerstens H, Habibi E, Gut M, Yaspo ML, Linser M, Lowy E, Datta A, Clarke L, Flicek P, Vingron M, Roos D, van den Berg TK, Heath S, Rico D, Frontini M, Kostadima M, Gut I, Valencia A, Ouwehand WH, Stunnenberg HG, Martens JHA, Kuijpers TW.

    Cell Rep. 2018 Sep 4;24(10):2784-2794. doi: 10.1016/j.celrep.2018.08.018.

  • Lamin B1 mapping reveals the existence of dynamic and functional euchromatin lamin B1 domains

  • Pascual-Reguant L, Blanco E, Galan S, Le Dily F, Cuartero Y, Serra-Bardenys G, Di Carlo V, Iturbide A, Cebrià-Costa JP, Nonell L, de Herreros AG, Di Croce L, Marti-Renom MA, Peiró S.

    Nat Commun. 2018 Aug 24;9(1):3420. doi: 10.1038/s41467-018-05912-z.

  • gemBS - high throughput processing for DNA methylation data from Bisulfite Sequencing

  • Merkel A, Fernández-Callejo M, Casals E, Marco-Sola S, Schuyler R, Gut IG, Heath SC.

    Bioinformatics. 2018 Aug 21. doi: 10.1093/bioinformatics/bty690. [Epub ahead of print]

  • Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis

  • Duruisseaux M, Martínez-Cardús A, Calleja-Cervantes ME, Moran S, Castro de Moura M, Davalos V, Piñeyro D, Sanchez-Cespedes M, Girard N, Brevet M, Giroux-Leprieur E, Dumenil C, Pradotto M, Bironzo P, Capelletto E, Novello S, Cortot A, Copin MC, Karachaliou N, Gonzalez-Cao M, Peralta S, Montuenga LM, Gil-Bazo I, Baraibar I, Lozano MD, Varela M, Ruffinelli JC, Palmero R, Nadal E, Moran T, Perez L, Ramos I, Xiao Q, Fernandez AF, Fraga MF, Gut M, Gut I, Teixidó C, Vilariño N, Prat A, Reguart N, Benito A, Garrido P, Barragan I, Emile JF, Rosell R, Brambilla E, Esteller M.

    Lancet Respir Med. 2018 Aug 9. pii: S2213-2600(18)30284-4. doi: 10.1016/S2213-2600(18)30284-4. [Epub ahead of print]

  • SP140 regulates the expression of immune-related genes associated with multiple sclerosis and other autoimmune diseases by NF-κB inhibition

  • Karaky M, Fedetz M, Potenciano V, Andrés-León E, Codina AE, Barrionuevo C, Alcina A, Matesanz F.

    Hum Mol Genet. 2018 Aug 8. doi: 10.1093/hmg/ddy284. [Epub ahead of print]

  • On the path to extinction: Inbreeding and admixture in a declining grey wolf population

  • Gómez-Sánchez D, Olalde I, Sastre N, Enseñat C, Carrasco R, Marques-Bonet T, Lalueza-Fox C, Leonard JA, Vilà C, Ramírez O.

    Mol Ecol. 2018 Aug 3. doi: 10.1111/mec.14824. [Epub ahead of print]

  • Deep analysis of acquired resistance to FGFR1 inhibitor identifies MET and AKT activation and an expansion of AKT1 mutant cells

  • Gimenez-Xavier P, Pros E, Aza A, Moran S, Tonda R, Esteve-Codina A, Dabad M, Sanchez-Cespedes M.

    Oncotarget. 2018 Jul 31;9(59):31549-31558. doi: 10.18632/oncotarget.25862. eCollection 2018 Jul 31.

  • Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species

  • Anastasiadi D, Esteve-Codina A, Piferrer F.

    Epigenetics Chromatin. 2018 Jun 29;11(1):37. doi: 10.1186/s13072-018-0205-1.

  • MET-oncogenic and JAK2-inactivating alterations are independent factors that affect regulation of PD-L1 expression in lung cancer

  • Saigi M, Alburquerque-Bejar JJ, McLEER-Florin A, Pereira C, Pros E, Romero OA, Baixeras N, Esteve-Codina A, Nadal E, Brambilla E, Sanchez-Cespedes M.

    Clin Cancer Res. 2018 Jun 13. pii: clincanres.0267.2018. doi: 10.1158/1078-0432.CCR-18-0267. [Epub ahead of print]

  • Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization

  • Kojic A, Cuadrado A, De Koninck M, Giménez-Llorente D, Rodríguez-Corsino M, Gómez-López G, Le Dily F, Marti-Renom MA, Losada A.

    Nat Struct Mol Biol. 2018 Jun;25(6):496-504. doi: 10.1038/s41594-018-0070-4. Epub 2018 Jun 4.

  • bigSCale: an analytical framework for big-scale single-cell data

  • Iacono G, Mereu E, Guillaumet-Adkins A, Corominas R, Cuscó I, Rodríguez-Esteban G, Gut M, Pérez-Jurado LA, Gut I, Heyn H.

    Genome Res. 2018 Jun;28(6):878-890. doi: 10.1101/gr.230771.117. Epub 2018 May 3.

  • Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia

  • Singh AA, Petraglia F, Nebbioso A, Yi G, Conte M, Valente S, Mandoli A, Scisciola L, Lindeboom R, Kerstens H, Janssen-Megens EM, Pourfarzad F, Habibi E, Berentsen K, Kim B, Logie C, Heath S, Wierenga ATJ, Clarke L, Flicek P, Jansen JH, Kuijpers T Yaspo ML, Valle VD, Bernard O, Gut I, Vellenga E, Stunnenberg HG, Mai A, Altucci L, Martens JHA.

    Oncotarget. 2018 May 22;9(39):25647-25660. doi: 10.18632/oncotarget.25429. eCollection 2018 May 22.

  • Combined HAT/EZH2 modulation leads to cancer-selective cell death

  • Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-Megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L.

    Oncotarget. 2018 May 22;9(39):25630-25646. doi: 10.18632/oncotarget.25428. eCollection 2018 May 22.

  • The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

  • Beekman R, Chapaprieta V, Russiñol N, Vilarrasa-Blasi R, Verdaguer-Dot N, Martens JHA, Duran-Ferrer M, Kulis M, Serra F, Javierre BM, Wingett SW, Clot G, Queirós AC, Castellano G, Blanc J, Gut M, Merkel A, Heath S, Vlasova A, Ullrich S, Palumbo E, Enjuanes A, Martín-García D, Beà S, Pinyol M, Aymerich M, Royo R, Puiggros M, Torrents D, Datta A, Lowy E, Kostadima M, Roller M, Clarke L, Flicek P, Agirre X, Prosper F, Bau T, Delgado J, López-Guillermo A, Fraser P, Yaspo ML, Guigó R, Siebert R, Martí-Renom MA, Puente X, LópezOtín C, Gut I, Stunnenberg HG, Campo E, Martin-Subero JI

    Nat Med. 2018 May 21. doi: 10.1038/s41591-018-0028-4. [Epub ahead of print]

  • Evaluating the Genetics of Common Variable Immunodeficiency: Monogenetic Model and Beyond

  • de Valles-Ibáñez G, Esteve-Solé A, Piquer M, González-Navarro E, Hernandez-Rodriguez J, Laayouni H, González-Roca E, Plaza-Martin AM, Deyà-Martínez Á, Martín-Nalda A, Martínez-Gallo M, García-Prat M, Del Pino-Molina L, Cuscó I, Codina-Solà M, Batlle-Masó L, Solís-Moruno M, Marquès-Bonet T, Bosch E, López-Granados E, Aróstegui JI, Soler-Palacín P, Colobran R, Yagüe J, Alsina L, Juan M, Casals F.

    Front Immunol. 2018 May 14;9:636. doi: 10.3389/fimmu.2018.00636. eCollection 2018.

  • Whole genome sequencing in the search for genes associated with the control of SIV infection in the Mauritian macaque model

  • de Manuel M, Shiina T, Suzuki S, Dereuddre-Bosquet N, Garchon HJ, Tanaka M, Congy-Jolivet N, Aarnink A, Le Grand R, Marques-Bonet T, Blancher A.

    Sci Rep. 2018 May 8;8(1):7131. doi: 10.1038/s41598-018-25071-x.

  • PM20D1 is a quantitative trait locus associated with Alzheimer's disease

  • Sanchez-Mut JV, Heyn H, Silva BA, Dixsaut L, Garcia-Esparcia P, Vidal E, Sayols S, Glauser L, Monteagudo-Sánchez A, Perez-Tur J, Ferrer I, Monk D, Schneider B, Esteller M, Gräff J.

    Nat Med. 2018 May;24(5):598-603. doi: 10.1038/s41591-018-0013-y. Epub 2018 May 7.

  • Recessive variants of MuSK are associated with late onset CMS and predominant limb girdle weakness

  • Owen D, Töpf A, Preethish-Kumar V, Lorenzoni PJ, Vroling B, Scola RH, Dias-Tosta E, Geraldo A, Polavarapu K, Nashi S, Cox D, Evangelista T, Dawson J, Thompson R, Senderek J, Laurie S, Beltran S, Gut M, Gut I, Nalini A, Lochmüller H.

    Am J Med Genet A. 2018 Apr 28. doi: 10.1002/ajmg.a.38707. [Epub ahead of print]

  • Deciphering the mechanism of action of 089, a compound impairing the fungal cell cycle

  • Stefanini I, Rizzetto L, Rivero D, Carbonell S, Gut M, Heath S, Gut IG, Trabocchi A, Guarna A, Ben Ghazzi N, Bowyer P, Kapushesky M, Cavalieri D

    Sci Rep. 2018 Apr 13;8(1):5964. doi: 10.1038/s41598-018-24341-y.

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